Calcium Carbonate and Sodium Chloride for Preventing Dentin Hypersensitivity and Gum Diseases
박용덕, 안효광, 권하정, 김찬호, Chae Sang-Kyun, 김유진, 김왕기, 황경숙,
소속 상세정보
박용덕 ( Park Yong-Duk ) - Kyung Hee University School of Dentistry Institue of Oral Biology Department of Preventive and Social Dentistry
안효광 ( Ahn Hyo-Kwang ) - Kyung Hee University School of Dentistry Institue of Oral Biology Department of Preventive and Social Dentistry
권하정 ( Kwon Ha-Jeong ) - Kyung Hee University School of Dentistry Institue of Oral Biology Department of Preventive and Social Dentistry
김찬호 ( Kim Chan-Ho ) - Amorepacific Company Department of Personal Care Research
( Chae Sang-Kyun ) - Amorepacific Company Department of Personal Care Research
김유진 ( Kim Yoo-Jin ) - Amorepacific Company Department of Personal Care Research
김왕기 ( Kim Wang-Gi ) - Amorepacific Company Department of Personal Care Research
황경숙 ( Hwang Kyung-Suk ) - Shinhan University Department of Dental Technology
KMID : 1157520140100020074
Abstract
Objective: The purpose of this study was to test the efficacy and safety of dentifrice containing sodium alginate, fine calcium carbonate and sodium chloride which has effects of reducing dental hypersensitivity and anti-inflammatory effects.
Methods: Human dentin specimens obtained from extracted molars were embedded with an acrylic resin and etched with citric acid. The Specimens were stored in phosphate buffered saline buffer before being brushed 1 minute only with test dentifrices. Samples were analyzed by scanning electron microscopy. In clinical tests, 41 Korean adults brushed with dis-tributed dentifrice for three month the run-in period of two weeks. The improvements were compared between control and experimental groups using mixtures with sodium alginate, calcium carbonate and sodium chloride in different concen-trations.
Results: The efficacy of dentin occlusion of dentin tubules rises as Na-alginate and calcium carbonate contents increase. The occlusion efficacy in the experimental dentifrice is 5 times better than the control. Over three-month period, the test group showed 64.4% improvements based on the initial value and 86.5% improvements compared to the control group in the re-duction of dentin hypersensitivity (p＜0.05). In the gingival index, the test group showed 38.1% improvements based on the initial value and 76.7% improvements compared to the control group (p＜0.05).
Conclusion: The ingredients of sodium alginate and calcium carbonate to reduce dentin hypersensitivity and sodium chlor-ide and cetylpyridinium chloride to prevent gingivitis were indeed effective in protecting sensitive gingival. No side effects were found throughout the whole body including the oral cavity of the subjects.
키워드
dentifrices; hypersensitivity; sodium alginate; calcium carbonate; sodium chloride; cetylpyridinium
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